Tetrahydrocannabinol is the main psychoactive component of cannabis and one of at least 113 total cannabinoids identified in the plant. Although the chemical formula of THC describes multiple isomers, the term THC generally refers to the. Le Herbe's unflavored THCA powder blends perfectly with freshly roasted coffee, espresso, artisanal chocolate, freshly baked baked goods, desserts, molecular cuisine and much more. THCA is found in varying amounts in fresh and undried cannabis, but it is progressively decarboxylated to THC upon drying, and especially under intense heating, such as when cannabis is smoked or cooked to convert it into cannabis edibles.
THCA in its isolated form is available for purchase at some medical and recreational cannabis dispensaries in the form of white crystalline powder.
Tetrahydrocannabinolic acid(THCA, 2-COOH-THC; conjugate-based tetrahydrocannabinolate) is a precursor to tetrahydrocannabinol (THC), an active component of cannabis. A study found that THCA and unheated Cannabis sativa extracts exert an immunomodulatory effect, not mediated by pathways coupled to the CB1 and CB2 receptors of cannabinoids, such as THC. THCA is rarely consumed directly, but its presence is usually tested when analyzing the presence of THC in cannabis or hemp-based products; some countries require that it be measured in such tests.
Sativa flowers were extracted with ethanol, and it was found that the anti-inflammatory activity of cannabis extracts is derived from the THCA present in fraction 7 (F) of the extract. THCA is also sometimes encapsulated and taken as a supplement for a variety of diseases, although there are currently no established medical applications. The conversion of THCA to THC in vivo seems to be very limited, giving it a very mild efficacy as a THC prodrug. THCA was able to inhibit the levels of tumor necrosis factor alpha (TNF-alpha) in U937 macrophages and peripheral blood macrophages, an inhibition that persisted for a longer period of time, while after a prolonged period of exposure, THC and the heated extract tend to induce the level of TNF-alpha.
In fact, if someone has a little bit of almost pure crystalline THC and an almost pure THC distillate they can measure us. Sativa, at a certain combination of concentrations, shows a significant increase in cytotoxic activity and suppresses the expression of the COX-2 and MMP9 genes both in cell culture and in colon tissue. This suggests that the anti-inflammatory activity of cannabis extracts in colonic epithelial cells is derived from a fraction of the extract that contains THCA and is mediated, at least partially, by the GPR55 receptor. Therefore, any laboratory analysis of THCA that uses any technique that involves significant heat will generate THC in the process of manipulation and analysis.
Enjoy a healthy nutrition label, fast-acting THCA (5 to 10 minutes), predictable compensatory effects (1 to 4 hours) and the most bioavailable THCA in the world. It has two isomers, THCA-A, in which the carboxylic acid group is in position 1, between the hydroxy group and the carbon chain, and THCA-B, in which the carboxylic acid group is in position 3, following the carbon chain.